abstract：OBJECTIVE:The aim of this study was to evaluate whether there was an association between pathology type and ERCC1, BRCA1, RRM1, TUBB3, STMN1, TOP2A and epidermal growth factor receptor (EGFR) messenger ribonucleic acid (mRNA) expression level in Chinese patients with non-small cell lung carcinoma (NSCLC). MATERIALS AN...

journal_title：Journal of cancer research and therapeutics

authors： Chen G,Jundong GU,Chen J,Liu Y,Song Z

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To study the clinical results and prognostic factors of patients with glioblastoma multiforme (GBM) treated by postoperative radiation therapy (PORT) and concomitant temozolomide followed by adjuvant temozolomide. METHODS:From 2005 to 2008, 215 patients (median age 48 years) with GBM were treated with PORT p...

journal_title：Journal of cancer research and therapeutics

authors： Julka PK,Sharma DN,Mallick S,Gandhi AK,Joshi N,Rath GK

更新日期：2013-07-01 00:00:00

abstract：AIM:This study was aimed to assess the in vivo anti-tumoral potency of the novel 6-nitro-2-(3-chloropropyl)-1H-benz[de]isoquinoline-1,3-dione [Compound 1] that has earlier demonstrated excellent cytotoxicity in 15 out of 17 human tumor cell lines tested. MATERIALS AND METHODS:Two murine tumors namely Sarcoma-180 (S-18...

journal_title：Journal of cancer research and therapeutics

authors： Mukherjee A,Dutta S,Sanyal U

更新日期：2013-07-01 00:00:00

abstract：:The mixed lineage leukemia (MLL) gene at chromosome band 11q23 is commonly involved in reciprocal translocations that is detected in acute leukemia. The MLL gene, commonly known as mixed lineage leukemia or myeloid lymphoid leukemia, has been independently identified and cloned from the 11q23 breakpoint of acute leuke...

journal_title：Journal of cancer research and therapeutics

authors： Goud KI,Dayakar S,Prasad SV,Rao KN,Shaik A,Vanjakshi S

更新日期：2013-07-01 00:00:00

abstract：:Hodgkin's lymphoma of the breast is very rare. We report a case of Hodgkin's lymphoma of the breast in a 61 year old post-menopausal female who presented with a 3 month history of left breast painless lump. Excision biopsy was done and histology showed nodular sclerotic Hodgkin's lymphoma confirmed by immunohistochemi...

journal_title：Journal of cancer research and therapeutics

authors： Osuji CU,Ahaneku GI,Onwubuya EI,Okocha EC,Ukah C,Emegoakor CD,Omejua EG

更新日期：2013-07-01 00:00:00

abstract：CONTEXT:Free radical associated damages play a major role in causation of cancer in tobacco habituates. The free radicals released by tobacco bring about alterations in antioxidant levels in humans and these free radical associated damages are reflected through antioxidant enzyme activities in blood. AIMS:To evaluate ...

journal_title：Journal of cancer research and therapeutics

authors： Naga Sirisha CV,Manohar RM

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Activating mutations in the epidermal growth factor (EGFR) gene confer sensitivity to the tyrosine kinase inhibitors (TKIs) in patients with advanced non-small cell lung cancer (NSCLC). TKI treatment efficacy and EGFR mutation implications were evaluated in clinically selected advanced NSCLC patients treated...

journal_title：Journal of cancer research and therapeutics

authors： Ovcaricek T,Cufer T,Kern I,Sodja E,Sadikov A

更新日期：2013-04-01 00:00:00

abstract：:Intra-nodal palisaded myofibroblastoma (IPM) is a rare benign lymph node mesenchymal tumor. It presents as a slow growing, painless nodular mass confined mostly to the inguinal area. Histologically, it shows palisading spindle cells, hemorrhages, hemosiderin laden macrophages, and amianthoid fibers, almost totally rep...

journal_title：Journal of cancer research and therapeutics

authors： Sarma NH,Arora KS,Varalaxmi KP

更新日期：2013-04-01 00:00:00

abstract：:Primary neuroendocrine carcinoma of the female genital tract is a rare entity with aggressive clinical behavior and a poor prognosis. This kind of malignancy arising in the vagina is extremely rare. We report a case of primary neuroendocrine carcinoma of vagina arising in a setting of atypical vaginal adenosis. ...

journal_title：Journal of cancer research and therapeutics

authors： Khurana A,Gupta G,Gupta M,Kaur M

更新日期：2013-04-01 00:00:00

abstract：CONTEXT:Cervical cancer is a preventable disease; it is the primary cancer amongst women in South Africa. AIMS:The objective of this study is to assess the awareness and detection methods of cervical cancer. SETTINGS AND DESIGN:This was a cross-sectional study conducted among 180 full time final year undergraduate fe...

journal_title：Journal of cancer research and therapeutics

authors： Hoque ME

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Tobacco use has been associated with various carcinomas including lung, esophagus, larynx, mouth, throat, kidney, bladder, pancreas, stomach, and cervix. Biomarkers such as concentration of cotinine in the blood, urine, or saliva have been used as objective measures to distinguish nonusers and users of tobac...

journal_title：Journal of cancer research and therapeutics

authors： Balhara YP,Jain R

更新日期：2013-01-01 00:00:00

abstract：:Renal cell carcinoma is the most frequent kidney neoplasm, with a high tendency to metastasize. The occurrence of renal carcinoma metastasis to the head and neck region is extremely rare. Here we present one such case where the tongue metastasis was the initial presenting feature of disease. ...

journal_title：Journal of cancer research and therapeutics

authors： Ray A,Bhattacharya J,Ganguly S

更新日期：2013-01-01 00:00:00

abstract：:We report a known case of adenoid cystic carcinoma of right parotid gland in a 36-year-old Indian male, diagnosed 5 years ago for which he underwent surgery followed by radiotherapy. Now the patient has presented to the surgical oncologist with a mass near angle of right jaw. Computed tomography (CT) performed elsewhe...

journal_title：Journal of cancer research and therapeutics

authors： Tewari A,Padma S,Sundaram PS

更新日期：2013-01-01 00:00:00

abstract：CONTEXT:The compound 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) has been isolated from several different plant species, including Petroselinum sativum. Our recent study found that apiole is a chemical derivative of 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1), which has been isolated from dried Antrodi...

journal_title：Journal of cancer research and therapeutics

authors： Wei PL,Tu SH,Lien HM,Chen LC,Chen CS,Wu CH,Huang CS,Chang HW,Chang CH,Tseng H,Ho YS

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The integrity of the immune system is necessary to control tumor progression and a compromised state contributes to tumor escape. AIMS:The study intends to evaluate the presence and distribution pattern of Langerhans cells (LC) in Oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC) oral ...

journal_title：Journal of cancer research and therapeutics

authors： Upadhyay J,Rao NN,Upadhyay RB

更新日期：2012-10-01 00:00:00

abstract：:Lymphoma of the salivary gland accounts for 5% of cases of extranodal lymphoma and 10% of malignant salivary gland tumors. Most primary salivary gland lymphomas are B marginal zone lymphomas arising on a background of sialadenitis associated with an autoimmune disorder such as Sjorgen's syndrome. This report describes...

journal_title：Journal of cancer research and therapeutics

authors： Metikurke SH,Krishnappa R,Ramachar SM,Arora I

更新日期：2012-10-01 00:00:00

abstract：AIM:The aim of this study was to analyze the demographic features, reproductive history and stage at disease presentation among the female breast cancer patients. DESIGN AND SETTING:The present prospective hospital-based study was conducted in Department of Radiation Oncology, University Teaching and Tertiary Referral...

journal_title：Journal of cancer research and therapeutics

authors： Wani SQ,Khan T,Wani SY,Koka AH,Arshad S,Rafiq L,Mqabool LM,Afroz F

更新日期：2012-07-01 00:00:00

abstract：:Papillary carcinoma is a well-differentiated type of thyroid carcinoma with very good overall prognosis. The commonest site of metastases is the lymph node, distant metastases being rare. We present a case of a 52-year-old male who presented with a solitary metastasis in the left para-sellar region and cavernous sinus...

journal_title：Journal of cancer research and therapeutics

authors： Chandarana MN,Epari S,Chaukar D,Moiyadi AV

更新日期：2012-07-01 00:00:00

abstract：:Many oral lesions may need to be diagnosed by removing a sample of tissue from the oral cavity. Biopsy is widely used in the medical field, but the practice is not quite widespread in dental practice. As oral pathologists, we have found many artifacts in the tissue specimen because of poor biopsy technique or handling...

journal_title：Journal of cancer research and therapeutics

authors： Kumaraswamy KL,Vidhya M,Rao PK,Mukunda A

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:We performed this study to explore the association of computed tomography (CT) findings with outcomes of patients with non-small-cell lung cancer (NSCLC) treated with tyrosin kinase inhibitor (TKI) such as gefitinib or erlotinib. MATERIALS AND METHODS:We analyzed outcomes for 240 patients according to primary ...

journal_title：Journal of cancer research and therapeutics

authors： Na II,Choe du H,Kim CH,Park SH,Park JH,Lee JC

更新日期：2012-04-01 00:00:00

abstract：:Primary amyloidosis of bladder is a rare disease that closely resembles bladder cancer on clinical presentation with painless gross hematuria. Pathologically this is a totally benign non-neoplastic lesion and its association with urothelial carcinoma of the bladder is rare. We herein report a 64-year-old diabetic male...

journal_title：Journal of cancer research and therapeutics

authors： Gupta P,Hanamshetti S,Kulkarni JN

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Oral cancer is the third most common form of malignancies in India. In many cases it develops at the site of premalignant lesion. Transformation of normal tissue to premalignant lesion and further to oral cancer results in alteration in glycolytic pathway and hence the lactate dehydrogenase levels. Therefore...

journal_title：Journal of cancer research and therapeutics

authors： Shetty SR,Chadha R,Babu S,Kumari S,Bhat S,Achalli S

更新日期：2012-01-01 00:00:00

abstract：CONTEXT:Renal cell carcinoma (RCC) is a kidney cancer that originates in renal parenchyma and it is the most common type of kidney cancer with approximately 80% lethal cases. AIMS:To interpret the mechanism, explore the regulation of TF-target genes and TF-pathway, and identify the potential key genes of renal cell ca...

journal_title：Journal of cancer research and therapeutics

authors： Zhai W,Xu YF,Liu M,Zheng JH

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:The new diode Isorad was validated for intensity modulated radiotherapy (IMRT) and the observations during the validation are reported. MATERIALS AND METHODS:The validation includes intrinsic precision, post-irradiation stability, dose linearity, dose-rate effect, angular response, source to surface (SSD)...

journal_title：Journal of cancer research and therapeutics

authors： Kinhikar R,Chaudhari S,Kadam S,Dhote D,Deshpande D

更新日期：2012-01-01 00:00:00

abstract：:Foot is an uncommon site for chondrosarcoma and involvement of phalanges is extremely rare. Here, a case of low-grade chondrosarcoma of the distal phalanx of the right great toe in a 37-year-old male patient is being reported. The patient complained of gradual swelling of the right great toe and pain for last 2 years....

journal_title：Journal of cancer research and therapeutics

authors： Mondal SK

更新日期：2012-01-01 00:00:00

abstract：:We herein describe a case of drug-induced interstitial lung disease (ILD) following treatment with erlotinib. The plasma trough concentration of erlotinib at the time of the ILD diagnosis was extremely elevated compared with the plasma maximum concentration on day 1. We hypothesized that this phenomenon was associated...

journal_title：Journal of cancer research and therapeutics

authors： Tsubata Y,Hamada A,Sutani A,Isobe T

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:Management of recurrent presacral rectal cancer is often not amenable to curative surgery. The goal of this study is to evaluate the safety and efficacy of cyberknife stereotactic body radiotherapy (SBRT) in the management of presacral recurrences. MATERIALS AND METHODS:Between April 2003 and October 2008, 14 ...

journal_title：Journal of cancer research and therapeutics

authors： Defoe SG,Bernard ME,Rwigema JC,Heron DE,Ozhasoglu C,Burton S

更新日期：2011-10-01 00:00:00

abstract：CONTEXT:Biopsy Gleason score (b-GS) is often different from the Gleason score obtained after analysis of radical prostatectomy (RP) specimen (rp-GS). Upgradation has an important implication in decision making for cancer prostate management, and is the focus of this study. AIM:To evaluate Gleason score upgradation aft...

journal_title：Journal of cancer research and therapeutics

authors： Kulkarni JN,Valsangkar RS,Jadhav YR,Singh DP

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:This study was designed to evaluate inter and intraobserver concordance in gross tumor volume (GTV) delineation on megavoltage CT (MVCT) images in patients with postoperative vault recurrences. MATERIALS AND METHODS:Three observers delineated GTV on MVCT and CECT and two observers recontoured on MVCT images. T...

journal_title：Journal of cancer research and therapeutics

authors： Upasani M,Chopra S,Engineer R,Medhi S,Master Z,Mahantshetty U,Shrivastava SK

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Cancer, a disorder of cellular behavior is characterized by the alteration of serum glycoproteins, which are composed of different monosaccharides. One of the monosaccharides is l-fucose, a methyl pentose, which is the terminal sugar in most of the plasma glycoproteins. Elevated levels of protein-bound fucos...

journal_title：Journal of cancer research and therapeutics

authors： Parwani RN,Parwani SR

更新日期：2011-04-01 00:00:00

abstract：:Medullary thyroid carcinoma is a rare thyroid neoplasm that can be either sporadic or familial. It occurs in adults, presenting as a solitary cold nodule on thyroid scan. Most are solid, firm, and non-encapsulated, and occur in the mid portion or upper half of the thyroid gland, corresponding to areas with greater num...

journal_title：Journal of cancer research and therapeutics

authors： Santosh KV,Raychaudhuri S,Subramanya H,Naveen Kumar BJ

更新日期：2011-04-01 00:00:00

abstract：:Cutaneous metastasis from transitional cell bladder carcinoma is a rare clinical entity associated with poor prognosis. We present a case of cutaneous metastasis arising from a transitional cell bladder carcinoma in a male patient who had undergone a radical cystectomy and bilateral ureterostomy 17 months previously. ...

journal_title：Journal of cancer research and therapeutics

authors： Salemis NS,Gakis C,Zografidis A,Gourgiotis S

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Administering drugs outside the terms of their official labeling is called off-label use. In the West, oncologists often use drugs off-label, which offers several advantages especially while treating patients with multiple comorbidities or advanced cancer. The practice of off-label prescribing of anticancer ...

journal_title：Journal of cancer research and therapeutics

authors： Gota V,Patial P

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma is the most common primary tumor of the liver. Disease dissemination occurs through hematogenous routes and frequently involves the lungs, bone, adrenal glands, and pancreas. The patterns of the extrahepatic manifestations are diverse. Soft tissue metastasis is extremely rare and man...

journal_title：Journal of cancer research and therapeutics

authors： Michalaki V,Zygogianni A,Kouloulias V,Balafouta M,Vlachodimitropoulos D,Gennatas CG

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Changes in salivary flow rate were studied in head and neck (H and N) cancer patients who, after receiving moderately accelerated radiotherapy (RT) and concurrent chemotherapy (CT), were free of disease at 1 year. MATERIALS AND METHODS:Between July 2003 and July 2005, saliva estimation was performed for 36 ...

journal_title：Journal of cancer research and therapeutics

authors： Lal P,Bajpai R,Khurana R,Das KJ,Kumar P,Tiwari A,Gupta N,Kumar S

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Oral submucous fibrosis (OSF) is a chronic irreversible condition of the oral mucosa with proven malignant potential. However, till date, there has been a dearth of effective management strategies. This study used alpha lipoic acid, an antioxidant, in oral form to determine if it could be usef...

journal_title：Journal of cancer research and therapeutics

authors： Rao PK

更新日期：2010-10-01 00:00:00

abstract：:Choriocarcinoma is the most malignant tumor of gestational trophoblast origin. Metastasis to brain is considered a poor prognostic indicator. Recent advances in adjuvant radiotherapy and chemotherapy have led to an excellent outcome of these patients. Craniotomy is indicated in selected cases with cerebral metastases....

journal_title：Journal of cancer research and therapeutics

authors： Dadlani R,Furtado SV,Ghosal N,Prasanna KV,Hegde AS

更新日期：2010-10-01 00:00:00

abstract：AIM:To evaluate the integral dose to carotid vessels in extended field intensity modulated radiotherapy (IMRT) (including the lower neck nodes in IMRT field) and split field IMRT (using separate single anterior field to treat lower neck nodes) in cancer nasopharynx. MATERIALS AND METHODS:Dosimetric data from 10 patien...

journal_title：Journal of cancer research and therapeutics

authors： Bahl A,Basu KS,Sharma DN,Rath GK,Julka PK,Thulkar S

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Tumor markers are a major part of the secondary prevention and thus the detection of malignancies. Neoplasms often have an increased concentration of sialic acid on the tumor cell surface and are shed or secreted by some of these cells which increase the concentration in blood. MATERIALS AND METHODS:The stu...

journal_title：Journal of cancer research and therapeutics

authors： Joshi M,Patil R

更新日期：2010-07-01 00:00:00

abstract：:Radiofrequency ablation (RFA) recently has been applied to benign thyroid nodules, mainly for the cosmetic reasons, and limited cases of local recurrences or focal distant metastases of well-differentiated thyroid cancer, in the high-risk reoperative condition or for the palliative purpose. But no report has been made...

journal_title：Journal of cancer research and therapeutics

authors： Kim HY,Ryu WS,Woo SU,Son GS,Lee ES,Lee JB,Bae JW

更新日期：2010-07-01 00:00:00